Houston brings in the first runs

Both teams began the night quietly at the plate, with just a lone hit on each side through three innings. Houston fared better the second time through their lineup, starting with Jose Altuve, who led off the fourth with a walk, advanced to third on a double by Michael Brantley, then scored on an RBI-groundout by Alex Bregman, the first run of the season to give the Astros a 1-0 lead.

The reason for the quiet start for both offenses — an entertaining pitching matchup was unfolding against Chris Bassitt and Zack Greinke. While Bassitt allowed a run in the fourth, he was otherwise successful on the mound until the sixth, when he would be relieved after a one-out double followed by a walk. Both of those runs would eventually score, as later in the inning, Yordan Alvarez sent a fastball the opposite way off the left-field wall for a two-RBI double to extend the lead to 3-0.

Yordan adds two more to the scoreboard, its 3-0 #Astros
Stay up late and lets get another #OpeningDay win!#ForTheH pic.twitter.com/nATJuBdA0w
— AT&T SportsNet SW (@ATTSportsNetSW) April 2, 2021

Greinke cruises through six

For Houston, Greinke was on cruise control tossing six scoreless frames, during which he allowed only three hits and just one runner to make it to scoring position. It being just the first game of the season, Dusty Baker did not try to test him too far, going to his bullpen after six innings. Greinke's final line: 6.0 IP, 3 H, 0 R, 0 ER, 0 BB, 4 K, 82 P.

Enoli Paredes took over in the seventh, allowing Oakland's first run of the night and season after a leadoff double would come around on a sac-fly to make it a 3-1 game. Paredes would toss more pitches than he bargained for but eventually completed the frame with only the one run allowed.

Astros get the Opening Day victory

Michael Brantley took the run right back in the top of the eighth, leading the inning off with a solo home run to push the lead back to three runs. Alex Bregman made it back-to-back homers in the next at-bat, crushing one of his own 418 feet to the left-field stands, extending the lead to 5-1. Houston would load the bases on two walks and a pitch into Yordan Alvarez's back but left them stranded to keep the score there.

Joe Smith, who opted out of the 2020 season, made his return to regular-season play, coming in out of the bullpen for the bottom of the eighth. He faced four batters, getting two outs while allowing two hits before left-handed Blake Taylor would come in to counter lefty Matt Olson, who struck out to end the frame.

In the top of the ninth, former-Astro Reymin Guduan loaded the bases with no outs after a single and back-to-back walks to start things off. Kyle Tucker and Yordan Alvarez would both bring in runs on a sac fly, Michael Brantley scored on a wild pitch, and when the dust settled, it was now an 8-1 game. Ryne Stanek was given the bottom of the ninth with the large lead, which he would complete to finish off the win.