The Houston Astros return to action Wednesday night with a chance to get back on track and even their three-game set against the visiting Chicago White Sox. After falling 4–2 in Tuesday’s opener, the Astros now trail the season series 3–1 and will turn to Ryan Gusto (3-3, 4.78 ERA) in hopes of steadying the ship and reinforcing their grip on first place in the AL West.

Houston enters the matchup at 36–30 overall and 22–13 at home, a mark that reflects just how comfortable they've been playing in front of their fans. Though the offense has been inconsistent at times, the Astros are an impressive 19–4 when they manage to keep the ball in the yard — a stat that will be key with Gusto on the mound. The young right-hander has had an up-and-down season, but he'll be tasked with limiting a White Sox offense that did just enough to sneak away with a win in the opener.

Chicago, meanwhile, continues to play with a bit of unexpected edge despite sitting in last place in the AL Central. At 23–44, the White Sox have struggled most of the season — particularly on the road, where they’re just 7–26. Still, they've now won four of their last five games and will hand the ball to Sean Burke (3-6, 4.03 ERA), a righty who’s shown flashes of command and competitiveness in his rookie campaign.

The Astros will once again lean on their veterans to lead the way at the plate. Jose Altuve continues to be a consistent presence at the top of the lineup with nine home runs and 24 RBIs on the year. Yainer Diaz, who’s 10-for-39 with three home runs over his last 10 games, has started to find his swing again and could be a factor in the middle of the order. Houston will need more of that timely hitting if they want to avoid dropping their second straight at home — something that hasn’t happened often this year.

On the other side, Chase Meidroth has quietly become one of Chicago’s more reliable bats. Hitting .293 with five doubles and a pair of homers, Meidroth’s emergence adds some much-needed spark to a lineup that’s lacked consistency. Andrew Benintendi, hitting .257 over his last 10 games with four doubles, has also begun to warm up at the plate.

Both teams come in with nearly identical offensive production over their last 10 games — the Astros hitting .227 to the White Sox’s .226 — but Houston holds the edge in ERA at 3.44 compared to Chicago’s 4.04. That said, the Astros have been outscored by five runs over that stretch, and will need to clean up a few things on both sides of the ball to avoid falling into a mini-slide during this six-game homestand.

First pitch is set for 8:10 p.m. ET from Daikin Park, with Houston looking to reassert itself against a team it hasn’t solved yet this season. A win would not only even the series — it would also be a reminder that the Astros remain very much in control of their own narrative heading into the summer grind.

BETMGM SPORTSBOOK LINE: Astros -181, White Sox +150; over/under is 8 1/2 runs.

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