Houston Astros (43-42, second in the AL West) vs. Toronto Blue Jays (39-46, fifth in the AL East)

Toronto; Wednesday, 7:07 p.m. EDT

PITCHING PROBABLES: Astros: Ronel Blanco (8-3, 2.49 ERA, 1.01 WHIP, 84 strikeouts); Blue Jays: Yusei Kikuchi (4-8, 4.18 ERA, 1.31 WHIP, 93 strikeouts)

BETMGM SPORTSBOOK: LINE Astros -113, Blue Jays -107; over/under is 8 1/2 runs

BOTTOM LINE: The Toronto Blue Jays host the Houston Astros on Wednesday.

Toronto is 21-22 in home games and 39-46 overall. The Blue Jays have a 27-15 record in games when they record eight or more hits.

Houston has a 19-23 record on the road and a 43-42 record overall. Astros hitters have a collective .322 on-base percentage, the second-ranked percentage in the AL.

Wednesday’s game is the sixth meeting between these teams this season. The Astros hold a 3-2 advantage in the season series.

TOP PERFORMERS: Vladimir Guerrero Jr. leads the Blue Jays with a .298 batting average, and has 18 doubles, 13 home runs, 39 walks and 50 RBI. Isiah Kiner-Falefa is 16-for-38 with three home runs and four RBI over the past 10 games.

LAST 10 GAMES: Blue Jays: 4-6, .248 batting average, 5.69 ERA, outscored by six runs.

Astros: 8-2, .293 batting average, 3.70 ERA, outscored opponents by 27 runs

INJURIES: Blue Jays: Isiah Kiner-Falefa: 10-Day IL (knee), Vladimir Guerrero Jr.: day-to-day (finger), Yimi Garcia: 15-Day IL (elbow), Jordan Romano: 15-Day IL (elbow), Alek Manoah: 15-Day IL (elbow)

Astros: Jake Bloss: 15-Day IL (shoulder), Victor Caratini: 10-Day IL (hip), Justin Verlander: 15-Day IL (neck), Cristian Javier: 60-Day IL (forearm), Kyle Tucker: 10-Day IL (shin), Jose Urquidy: 60-Day IL (forearm), Oliver Ortega: 60-Day IL (elbow), Bennett Sousa: 60-Day IL (shoulder), Penn Murfee: 60-Day IL (elbow), Luis Garcia: 60-Day IL (elbow), Lance McCullers Jr.: 60-Day IL (elbow), Kendall Graveman: 60-Day IL (elbow)