
Jeremy Peña is having success hitting fourth. Photo by Kevin M. Cox/Getty Images.
The Houston Astros host the Toronto Blue Jays on Wednesday night looking to keep momentum rolling and hand the Jays their fifth straight loss. First pitch is set for 7:40 p.m. EDT at Daikin Park.
Both teams enter the matchup with nearly identical records—Houston at 12-11, Toronto at 12-12—but they’re trending in opposite directions. The Astros have won six of their last ten and boast an 8-6 record at home, while the Blue Jays have dropped four straight and are just 4-7 on the road.
Ryan Gusto gets the start for Houston, entering with a 2-1 record, a 3.18 ERA, and 17 strikeouts across three appearances. He’ll go up against Bowden Francis, who brings a 3.13 ERA and a 1.04 WHIP into the game, along with 20 strikeouts in his four starts.
Jeremy Peña continues to spark the Astros lineup with three homers and three doubles, while catcher Yainer Diaz has added timely hits despite a recent slump. For Toronto, George Springer leads the team with a .333 average, and Bo Bichette has been steady at the plate, going 14-for-45 over his last 10 games.
The Blue Jays have found success when they out-hit opponents, going 10-3 in those games—but Houston’s pitching staff has held opponents to just a 2.86 ERA over the past 10 outings.
The betting line has Toronto as slight road favorites at -120, with Houston at +100 and the over/under set at 8 runs.
Here's a look at tonight's lineup. Cam Smith gets the night off in right field, with Zach Dezenzo filling in. It appears Dezenzo's thumb is fine after banging it up sliding into second base a couple of night's ago.
Image via: MLB.com/Screenshot.
Jake Myers is also getting the night off as Chas McCormick gets the start in center. And Mauricio Dubon is getting the nod, starting over Brendan Rodgers at second base.
Astros turn it on late to beat A’s after McCullers strikes out 12
May 28, 2025, 5:11 pm
Zach Dezenzo homered and Victor Caratini drove in two runs in the seventh to help the Houston Astros rally for a 5-3 victory over the Athletics on Wednesday.
The Athletics led by 1 when rookie Justin Sterner (1-1) took over for Luis Severino to start the seventh. Dezenzo sent his fourth pitch 416 feet to center field for his second homer this season to tie it at 3-all.
DEZENZO. BOMB. #BuiltForThis pic.twitter.com/ur27VQMcmm
— Houston Astros (@astros) May 28, 2025
There were runners on second and third with two outs in the inning when Caratini lined a single to center field to score 2 and put the Astros on top 5-3.
CARATINI FOR THE LEAD! pic.twitter.com/QX8fAMlQcd
— Houston Astros (@astros) May 28, 2025
Houston’s Lance McCullers Jr. allowed five hits and three runs in a season-long six innings in his fifth start after missing more than two seasons with injuries.
Shawn Dubin (2-0) struck out two in a scoreless seventh for the win and Josh Hader converted his 14th save in 14 opportunities with a scoreless ninth.
Jacob Wilson homered with two RBIs for the Athletics, who fell to 3-17 in their last 20 games.
Severino yielded three hits and two runs — one earned — in six innings. He struck out four to give him 1,003 strikeouts in his career, making him the 48th active player to reach 1,000 strikeouts.
Christian Walker was hit on the hand with a pitch to start Houston’s fourth. He left in the bottom of the sixth inning because of the injury. Manager Joe Espada said the X-rays were negative after the game.
Key moment
The Astros jumping on Sterner in the seventh to take the lead after Severino’s strong start kept them in check through six.
Key stat
McCullers struck out 12 to tie a career high he last reached in 2018.
Lance McCullers, 12th K. 👏👏👏 pic.twitter.com/A3hJ0eSzId
— Rob Friedman (@PitchingNinja) May 28, 2025
Up next
LHP Jacob Lopez (0-2, 2.57 ERA) will start for Oakland on Thursday night in the opener of a four-game series at Toronto. The Astros open a four-game series against Tampa Bay on Thursday night with RHP Ryan Gusto (3-2, 4.58) on the mound against RHP Shane Baz (4-3, 4.94).